Disposition of Remifentanil in Obesity
A New Pharmacokinetic Model Incorporating the Influence of Body Mass
Tae Kyun Kim, M.D., Shinju Obara, M.D., Talmage D. Egan, M.D., and the Remifentanil Pharmacokinetics in Obesity Investigators
(Anesthesiology 2017; 126:1019-32)
When a pharmacokinetic or pharmacodynamic model is implemented in simulation